Contact us at: 1-866-6MGH-OCD or email@example.com
Transcranial Magnetic Stimulation (TMS) in Obsessive Compulsive Disorder (OCD): Mechanisms and biomarkers
PI: Joan Camprodon, M.D., Ph.D., M.P.H.
- Dylan Abrams
We are looking for adults with OCD between the ages of 18 and 65 in order to evaluate the safety and effectiveness of TMS in treating OCD. TMS is a noninvasive method in which a magnetic “coil” is placed near an individual’s head and delivers small electrical currents in the brain, stimulating brain cells that may relieve OCD symptoms. Research has demonstrated this treatment is effective in treating depression, and we would like to expand this research to OCD.
Pilot: Fear Extinction and Mechanisms of Change in Obsessive Compulsive Disorder
PIs: Sabine Wilhelm, Ph.D. & Mohammed R. Milad, Ph.D
- Valerie Braddick
- (617) 724-4354
The purpose of this study is to find out more about how the brain forms and stores emotional learning in obsessive-compulsive disorder (OCD). In particular, we would like to understand how human beings learn not to fear. We are also interested in learning about how behavioral therapy (BT) for OCD affects emotional learning in the brain. We hope this study will help us understand why people with OCD cannot control unwanted fear and to develop better treatments for adults with OCD. Patients will be randomly assigned (like the flip of a coin) to receive 12 weeks of BT or 12 weeks of waitlist, followed by 12 weeks of BT.
We are seeking individuals 18-60 with OCD and individuals with no psychiatric history. Participation includes a diagnostic evaluation, 12 weeks of BT or 12 weeks of waitlist followed by BT, questionnaires, and up to six (6) MRI scans. You may receive up to $500 for your participation and reimbursement for parking.
Effect of Intranasal Oxytocin on Social Cognition
PI: Sabine Wilhelm, Ph.D.
The Massachusetts General Hospital is seeking adults with Obsessive Compulsive Disorder and/or Body Dysmorphic Disorder to participate in a research study. If you are eligible, participation involves a clinical interview, questionnaires, use of two nasal sprays containing oxytocin and placebo, and computerized tasks. Women must not be pregnant and must be taking oral contraception. Participation includes three brief visits to MGH and up to $120 compensation.
Have you had a baby in the last 6 months?
Take a minute to ask yourself the following questions.
- Do you feel over-anxious all the time and not able to control it?
- Are you having thoughts that you can’t get out of your mind or are you unable to concentrate, feeling like your mind goes blank?
- Are you worried about a number of events and activities in particular about your baby?
- Do you feel more nervous or irritable or your muscles are very tense?
If you recognize yourself in any of these questions, please help us research and characterize obsessive compulsive symptoms in post-partum women. Participation involves completing a survey that takes no more than 20 minutes: https://limesurvey.partners.org/limesurvey/index.php/463814?lang=en
For more information, if you have any questions or problems with this study please email the Principal Investigator (Dr. Baer) at firstname.lastname@example.org