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Hi, I am a 35yo female with OCD. When OCD started (age 23), I remember having been very sick with bronchitis and the worst sore throat ever not long before onset of OCD symptoms. This would have been back in 2002 – I was sick in March and by September I was prescribed anti-depressants for OCD (no hx of mood issues prior). I've often wondered if what we now know as PANDAS might have been what triggered OCD for me (no family history for it, nor other mental illness).
If that's the case, is there any kind of testing that can be done to determine if there is an autoimmune issue causing/exacerbating OCD? Would it be unheard of to give IVIG a try? What's the best way to bring this up with my psychiatrist (not sure if he supports PANDAS-OCD pathology)?
Thank you so much for this support forum!!
it really is impossible to answer your questions as this time. It is possible that pans may be involved. i don't think any tests would help nail this down. a few adults have been given ivig in similar situations and some report positive results. since it is not given in a double blind fashion, it is hard to evaluate such reports. i have given a few adults antibiotics when they have a childhood history consistent with pans and they have currently noted worsening OCD in the context of an illness. obviously, it is clearer that antibiotics are indicated if an infection can be identified. if worsening OCD is the main symptom, using antibiotics is purely an experiment that would be frowned upon by some physicians. all best wishes,
Michael Jenike, MD