Dedicated to improving the standard of care for people suffering from OCD, BDD, Tics, Hoarding, Hair Pulling, Skin Picking, and ORS

Research Studies

Obsessive Compulsive Disorder (OCD)

 

Body Dysmorphic Disorder (BDD)

 

Hoarding Disorder

 

Trichotillomania (hair pulling disorder)

 

 


OCD Studies

Contact us at: 1-866-6MGH-OCD or ocdclinic@partners.org

Adult Studies

“A Family-Based Examination of Information Processing”

(PI: Noah Berman, Ph.D.)

Allie Sullivan
(617) 643-4387
ADSULLIVAN@mgh.harvard.edu

The purpose of this study is to examine the thinking styles of parents with OCD and those of their children.  OCD is a psychiatric illness characterized by persistent and intrusive obsessions and/or repetitive, time-consuming compulsions.  For this study, we are recruiting parents with OCD and his or her children (ages 11-17).  Your participation will include 1 phone visit and 1 clinic visit. The research study visits involve assessments of you and your child(ren), including: diagnostic interviews, questionnaires about various psychological experiences, and cognitive assessments. Parents will receive a $50 gift card for completing the diagnostic interviews and each family member that attends the clinic visit will receive an additional $25 gift card. Parking costs will also be reimbursed.

Detailed Study Description

“Transcranial Magnetic Stimulation (TMS) in Obsessive Compulsive Disorder (OCD): Mechanisms and biomarkers”

(PI: Joan Camprodon, M.D., Ph.D., M.P.H.)

Inquiries: 1-866-6MGH-OCD

We are looking for right-handed adults with OCD between the ages of 18 and 65 in order to evaluate the safety and effectiveness of TMS in treating OCD. TMS is a noninvasive method in which a magnetic “coil” is placed near an individual’s head and delivers small electrical currents in the brain, stimulating brain cells that may relieve OCD symptoms. Research has demonstrated this treatment is effective in treating depression, and we would like to expand this research to OCD.

“Pilot: Fear Extinction and Mechanisms of Change in Obsessive Compulsive Disorder”

(PIs: Sabine Wilhelm, Ph.D. & Mohammed R. Milad, Ph.D)

Katie Limoncelli

(617) 724-4354

KLIMONCELLI@mgh.harvard.edu

The purpose of this study is to find out more about how the brain forms and stores emotional learning in obsessive-compulsive disorder (OCD). In particular, we would like to understand how human beings learn not to fear. We are also interested in learning about how behavioral therapy (BT) for OCD affects emotional learning in the brain. We hope this study will help us understand why people with OCD cannot control unwanted fear and to develop better treatments for adults with OCD. Patients will be randomly assigned (like the flip of a coin) to receive 12 weeks of BT or 12 weeks of waitlist, followed by 12 weeks of BT. We are seeking right-handed individuals 18-60 with OCD and individuals with no psychiatric history. Participation includes a diagnostic evaluation, 12 weeks of BT or 12 weeks of waitlist followed by BT, questionnaires, and up to six (6) MRI scans. You may receive up to $500 for your participation and reimbursement for parking.

Pediatric Studies

No currently enrolling studies at this time.   Please check back with us soon.


BDD Studies

Contact us at: 1-877-4MGH-BDD or bdd@partners.org

Adult Studies

“Cognitive Behavioral Therapy and Supportive Psychotherapy for BDD”

(PI: Sabine Wilhelm, Ph.D.)

1-877-4MGH-BDD
BDD@PARTNERS.ORG

The purpose of this research study is to learn more about two different forms of therapy to help individuals with BDD: cognitive behavioral therapy (CBT), a promising new treatment for BDD, and supportive psychotherapy (SPT), the most commonly received therapy for BDD. The investigators would like to find out which treatment is more effective for BDD. Participants will be randomly assigned (like the flip of a coin) to receive 22 sessions (over 24 weeks) of either CBT or SPT.

Detailed Study Description

“Enhancing the Effectiveness of Behavior Therapy for Body Dysmorphic Disorder.”

(PI: Sabine Wilhelm, Ph.D.)

Allie Sullivan
(617) 643-4387
ADSULLIVAN@mgh.harvard.edu

In this research study we seek to investigate the effectiveness of D-cycloserine as a memory booster for Exposure and Response Prevention in the treatment of Body Dysmorphic Disorder. D-cycloserine is an antibiotic that has been used in the treatment of tuberculosis for over 20 years. Research so far demonstrates D-cycloserine does increase the effectiveness of Exposure and Response Prevention in the treatment of Obsessive Compulsive Disorder. We would like to expand this research with D-cycloserine to see if it is effective with body dysmorphic disorder.

Detailed Study Description

Muscle Dysmorphia and BDD

(PI: Aaron J. Blashill, Ph.D.)

Katie Limoncelli
(617) 724-4354
KLIMONCELLI@mgh.harvard.edu

This study is examining similarities and differences between body dysmorphic disorder (BDD), and a subtype of BDD called muscle dysmorphia, among men age 18 and older. Muscle dysmorphia involves an excessive preoccupation with thoughts that one’s body is not sufficiently lean and muscular, and frequently involves excessive weightlifting. We are interested in recruiting both men with muscle dysmorphia and those with non-muscle focused appearance concerns. This one-time study visit is at the MGH main campus, and will last for roughly 2 hours, and consist of an interview with a clinician and filling out questionnaires. You will be reimbursed $50.00 for the completion of the study visit.

Detailed Study Description

“Oxytocin Biomarker for Body Dysmorphic Disorder”

(PI: Sabine Wilhelm, Ph.D.)

Angelina Gomez
877-4MGH-BDD
bdd@partners.org

The Massachusetts General Hospital is seeking men who are very worried about how they look to participate in a research study. If you are eligible, participation involves blood draws, a clinical interview, questionnaires, and computerized tasks. Participation includes two brief visits to MGH and up to $100 compensation.

Detailed Study Description

 


Hoarding Disorder Study

Contact us at: 1-866-6MGH-OCD or ocdclinic@partners.org

“Collecting and Goal Oriented Behaviors”

(PI: Jessica Rasmussen, Ph.D.)

(866) 6MGH-OCD
ocdclinic@partners.org

The Massachusetts General Hospital is seeking volunteers to participate in a one- visit research study involving a diagnostic interview (at no cost) and computerized tasks. To participate in this study, you must:

-Have a diagnosis of Hoarding Disorder

-Be 18 – 75 years old

-Be in good general health

-Be fluent in English

-Be comfortable with and capable of using a computer

Participants will receive up to $100 ($25/hr) compensation for completing the study and reimbursement for parking.

“Risk Factors Associated with Childhood Hoarding Behaviors”

(PI: Sabine Wilhelm, Ph.D.)

Abigail Stark
617-643-6204
amstark@mgh.harvard.edu

The Massachusetts General Hospital is seeking volunteers to participate in a one-visit research study involving a diagnostic interview (at no cost) and testing. This study is for children ages 8-17 who have difficulties with saving and collecting behaviors, or problems with discarding items (toys, clothes, papers, etc.). Participants will receive up to $75 compensation for completing the study and reimbursement for parking.


Trichotillomania (hair pulling disorder) Study

Contact us at: 617-643-8464 or EECURLEY@mgh.harvard.edu

 “A Genetics Study of Trichotillomania and Chronic Hair Pulling”

(PI: Nancy Keuthen, Ph.D.)

Erin Curley
(617) 643-8464
EECURLEY@mgh.harvard.edu

Do you pull out your hair?

If so, you might be interested in the Genetics Study of Trichotillomania and Chronic Hair Pulling, sponsored by Massachusetts General Hospital. Researchers from Massachusetts General Hospital are conducting a research study to learn more about the genetics links in the development and maintenance of Trichotillomania and chronic hair pulling. You may be eligible if you are between 18-65 years of age and frequently pull out your hair.

We are enrolling individuals 18-65 years of age who have been diagnosed with Trichotillomania, or have chronic hair pulling.

Participation is divided into 3 parts:

  • An interview
  • Self-report questionnaires
  • DNA (blood or saliva) sample to be collected at your visit

Study participation is strictly voluntary and may require 2-4 hours per person. Upon completion of all study tasks, each participant will be paid $50 for his/her participation.